Abstract: Objective To analyze the high-risk status and influencing factors of cardiovascular disease among residents aged 35-75 in Zhongmou County, Henan Province, so as to provide reference data for prevention and control of cardiovascular disease. Methods Relying on the National Cardiovascular Disease Early Screening and Comprehensive Intervention Project, people aged aged 35-75 from the preliminary screening data of the cardiovascular disease project in Zhongmou County, Henan Province from January to December 2016 were used as research subjects to conduct questionnaire surveys, physical fitness inspection and blood biochemical index detection. According to the “China Cardiovascular Disease Report 2015” and applying the China-PAR risk assessment model for cardiovascular disease risk assessment, using descriptive epidemiological analysis method to analyze the high-risk status of cardiovascular disease in this population, and univariate and multivariate analysis methods were used to analyze the high-risk factors of cardiovascular disease. Results A total of 2 104 residents were studied, including 1 122 males and 982 females; aged 35-75 years, with an average of （59.3±6.4） years; body mass index （BMI） was 17.1 -27.4 kg/m², with an average of （22.6±3.1） kg/m². Among them, 228 cases of high-risk cardiovascular disease were detected, and the detection rate was 10.84%. Of which the high-risk of high blood pressure accounted for the highest proportion （36.84%）, followed by the high-risk of cardiovascular disease （26.32%）, the high-risk of disease risk ≥20% （20.18%）, and the high-risk of dyslipidemia （16.67%）. Multivariate Logistic regression analysis showed that male （OR=2.499）, older age （OR=2.795）, BMI≥24.0 kg/m² （OR=2.255）, rural residence （OR=2.044）, junior high school and below and high school education or technical secondary school （OR=1.866, 1.383）, excessive drinking （OR=1.994）, physical exercise 1-2 times/week （OR=0.581） and ≥3 times/week （OR=0.489） were influencing factors of high-risk of cardiovascular disease among residents aged 37-75. Conclusion The detection rate of high-risk population of cardiovascular disease among residents aged 35-75 in Zhongmou County, Henan province is relatively high, it is affected by gender, age, BMI, residence, education, occupation, drinking and physical exercise. It is necessary to strengthen education and focus on screening for the population with the above influencing factors, and do a good job in early prevention, early detection and early treatment to reduce the harm of cardiovascular disease.

Key words: Cardiovascular disease, High-risk population, Screening, Influencing factor