Abstract: Objective To investigate the prevalence of musculoskeletal disorders among nursing staff in medical institutions and analyze the influencing factors, so as to guide the development of effective interventions. Methods The musculoskeletal disorder questionnaire was used to evaluate the musculoskeletal disorders of nursing staff in the hospital from February to June 2021, at the same time, the ergonomic load level was carried out according to the rapid upper limb assessment method, the demographic data of nursing staff were collected, and the influencing factors of musculoskeletal disorders were analyzed. Results Finally, 1 031 nursing staff were included, and the prevalence rate of musculoskeletal disorders was 77.21%, especially in neck, shoulder and waist. Multivariate Logistic regression analysis showed that age （OR=1.520）, body mass index ≥24.0 kg/m² （OR=1.960）, fertility history （OR=1.114）, working age （OR=2.208）, hospital level （OR=2.751）, departments （internal medicine： OR=0.451, pediatrics： OR=0.671, obstetrics and gynecology： OR=0.184, emergency： OR=2.487, other departments： OR=0.191）, and ergonomic load grade （OR=2.560） were the influencing factors of musculoskeletal disorders in nursing staff. Conclusion The prevalence rate of musculoskeletal disorders in nursing staff is at a high level, which is affected by many factors. Intervention measures should be taken to help nursing staff reduce adverse working posture, improve working environment, then reduce the prevalence rate of musculoskeletal disorders and improve the health condition of medical staff.

Key words: Hospital, Nursing staff, Muscle, Skeleton, Prevalence rate, Influencing factor