Abstract: Objective To investigate the compliance of folic acid supplementation and its influencing factors among women of childbearing age in Luzhou City, and to provide scientific basis for formulating the intervention measures of folic acid supplementation. Methods From June to December 2020, a total of 38 townships or community health service centers in 7 counties and districts including Jiangyang District, Naxi District and Luxian in Luzhou City, Sichuan Province were selected by convenience sampling method to recruit children aged 1 year or younger. The mothers of children who were vaccinated were taken as the survey subjects to conduct a questionnaire survey on “Folic Acid Awareness and Folic Acid Consumption in Women of Childbearing Age”. The results were analyzed by descriptive analysis method, and the influencing factors of folic acid supplementation compliance were analyzed by univariate and multivariate analysis methods. Results The age of 709 women of childbearing age was 20-47 years old, with an average age of （32.09±6.51） years. A total of 307 women （43.30%） had pre-pregnancy eugenic health check. Among the respondents, 84.76% had taken folic acid, and 32.02% correctly knew the purpose of folic acid supplementation, while the standard use of folic acid from the 3 months before pregnancy to the first 3 months of pregnancy only accounted for 19.46%. Multivariate Logistic regression analysis showed that the educational level of college or above （OR=2.158）, the monthly family income >3 000 yuan （OR=2.502）, the employees of government agencies and institutions （OR=3.543）, and the staff of enterprises （OR=2.776）, childbirth twice （OR=1.793） and ≥ 3 times （OR=2.504）, the pre-pregnancy eugenic health check （OR=4.586）, and the awareness of folic acid knowledge （OR=8.499） were promoting factors for compliance of folic acid supplementation among women of childbearing age in Luzhou. Conclusion The awareness of folic acid and the compliance rate of folic acid supplementation before pregnancy are low in women of childbearing age. Strengthening the awareness of folic acid preventing neural tube defects and the publicity and education of folic acid supplement health knowledge are useful to improve the compliance of folic acid supplement before pregnancy.

Key words: Woman of childbearing age, Folic acid, Medication compliance, Influence factor