Abstract: Objective To explore the influencing factors of recurrent abortion, and to provide the basis for the prevention of recurrent abortion. Methods Patients with recurrent abortion in a hospital in Dazhou City, Sichuan Province from October 2017 to December 2019 were selected as the study group, pregnant women with similar age and without spontaneous abortion in the same hospital in the same period were selected as the control group. The basic conditions, diet,disease status, abortion history, pregnancy conditions, uterine development and immune indicators were compared between the two groups. Results A total of 169 patients with recurrent abortion were enrolled in study group, 162 were in the control group, and the age of both groups was 26-38 years old. Multivariate logistic regression analysis showed that pregnant women with pre-pregnancy BMI≥27.0 （OR=3.316）, reproductive tract infection （OR=2.449）, hyperprolactinemia （OR=4.186）, luteal insufficiency （OR=2.833）, hypothyroidism （OR=1.314）, PCOS （OR=1.727）, artificial abortion history ≥3 times （OR=3.719）, bicornate uterus （OR=1.843）, too small uterus （OR=2.541）, occupational noise exposure （OR=6.759）, anti-phospholipid antibody （OR=4.836）, antinuclear antibody （OR=3.452）, antiendometrium antibody （OR=2.949）, antisperm antibody （OR=2.170） and irregular work and rest （OR=5.930） had a higher risk of recurrent abortion, while those with college degree or above （OR=0.321） and folic acid supplementation during pregnancy （OR=0.692） had a lower risk of recurrent abortion. Conclusion There are many risk factors for recurrent abortion. We should strengthen the education of fertility-related knowledge and the pre-pregnancy examinations for women of childbearing period. For women of childbearing period with risk factors, we should strengthen the monitoring and detection of reproductive health related items to avoid recurrent abortion.

Key words: Recurrent abortion, Risk factor, Prevention, Influencing factor