广东省诺如病毒急性胃肠炎疾病负担研究

doi:10.12183/j.scjpm.2020.0597

Abstract

Abstract: Objective To estimate the epidemiological burden of norovirus （NoVs） acute gastroenteritis in Guangdong Province, so as to provide scientific basis for formulating or adjusting epidemic prevention and control strategies.Methods Using data from infectious diarrheal disease surveillance, diarrhea related surveillance, and investigation results in Guangdong Province from 2013 to 2017, the epidemiological burden of NoVs acute gastroenteritis was assessed by morbidity, disability adjusted life years （ DALYs）, and the ratio of the number of cases reported by the internet to the number of actual incidence cases.Results The total number of cases of NoVs infectious gastroenteritis was 3.1027 million persons/year （2.535 9-4.037 6 million persons/year） in Guangdong Province from 2013 to 2017. The annual average number of medical visits was estimated to be 1.278 3 million persons/year （1.044 8-1.663 5 million persons/year）. The annual average number of inpatients was estimated to be 383 persons/year （313-499 persons/year）. The ratio of the number of cases reported by the internet to the number of actual incidence cases was 1∶1 203 （1∶860-1∶1 771）. The average total annual burden was 19 200.55 DALYs（16 919.20-25 001.83 DALYs）, and the per capita burden was 0.18 DALYs/thousand person-years （0.15-0.23 DALYs/thousand person-years）.Conclusion The burden of acute gastroenteritis caused by NoVs was high in Guangdong Province. It is necessary to strengthen the management of prevention and control, as well as the publicity and education.

Key words: Norovirus, Disease burden, Acute gastroenteritis

CLC Number:

R183.4

ZHANG Meng, XIANG Ying-fei, CHEN Jian-qian, LI Meng, YANG Fen, HUANG Qiong, ZHANG Yong-hui. Burden of acute gastroenteritis caused by norovirus in Guangdong Province[J].South China Journal of Preventive Medicine, 2020, 46(6): 597-600.

References

[1] Robilotti E, Deresinski S, Pinsky BA.Norovirus[J]. Clin Microbiol Rev,2015,28(1):134-164.
[2] Lysen M, Thorhagen M, Brytting M, et al.Genetic diversity among food-borne and waterborne norovirus strains causing outbreaks in Sweden[J]. J ClinMicrobiol,2009,47(8):2411-2418.
[3] Marks PJ, Vipond IB, Carlisle D, et al.Evidence for airborne transmission of norwalk-like virus(NLV) in a hotel restaurant[J]. Epidemiol Infect,2000,124:481-487.
[4] Wikswo ME, Hall AJ.Outbreaks of acute gastroenteritis transmitted by person-to-person contact-United States,2009-2010[J]. MMWR Surveill Summ,2012,61(9):1-12.
[5] Verhoef L, Hewitt J, Barclay L, et al.Norovirus genotype profiles associated with foodborne transmission,1999-2012[J]. Emerg Infect Dis,2015,21(4):592-599.
[6] 宋夏,刘弘. 诺如病毒的流行病学研究进展[J]. 上海预防医学,2017,29(4):261-272.
[7] Hall AJ, Vinje J, Lopman B, et al.Updated norovirus outbreak management and disease prevention guidelines[J]. MMWR Recomn Rep,2011,60(3):1-18.
[8] Ahmed SM, Hall AJ, Robinson AE, et al.Global prevalence of norovirus in cases of gastroenteritis: A systematic review and meta-analysis[J]. Lancet Infect Dis,2014,14(8):725-730.
[9] Patel MM, Hall AJ, Vinje J, et al.Noroviruses: a comprehensive review[J]. J Clin Virol,2009,44(1):1-8.
[10] Korte S, Pettke A, Kossow A, et al.Norovirus outbreak management: how much cohorting is necessary[J].J Hosp Infect,2016,92(3):259-262.
[11] Lopman BA, Steele D, Kirkwood CD, et al.The vast and Varied Global burden of norovirus: prospects for prevention and control[J]. PLoS Med,2016,13(4):e1001999.
[12] Gastanaduy PA, Hall AJ, Curns AT, et al.Burden of norovirus gastroenteritis in the ambulatory setting-United States, 2001-2009[J]. J Infect Dis,2013,207(7):1058-1065.
[13] Hall AJ, Lopman BA, Payne DC, et al.Norovirus disease in the United States[J]. Emerg Infect Dis,2013,19(8):1198-1205.
[14] Verhoef L, Koopmans M, Vanpelt W, et al.The estimated disease burden of norovirus in the Netherlands[J]. Epidemiol Infect,2013,141(3):496-506.
[15] 万壮, 黄琼, 张永慧, 等. 广州市诺如病毒感染性胃肠炎疾病负担评估[J]. 中华疾病控制杂志,2016,20(11):1135-1138.
[16] Scallan E, Griffin PM, Angulo FJ, et al.Foodborne illness acquired in the United States unspecified agents[J]. Emerg Infect Dis,2011,17(1):16-22.
[17] Zhou HL, Zhen SS, Wang JX, et al.Burden of acute gastroenteritis caused by norovirus in China: A systematic review[J]. J Infection,2017,75(3):216-224.
[18] 段胜钢,陆冬磊,罗宝章,等. 上海市诺如病毒感染性腹泻疾病负担的评估[J]. 中国食品卫生杂志,2017,29(6):676-679.
[19] Lian Y, Wu S, Luo L, et al.Epidemiology of norovirus outbreaks reported to the public health emergency event surveillance system, China, 2014-2017[J]. Viruses,2019,11(4):E342.
[20] Bartsch SM, Lopman BA, Ozawa S, et al.Global economic burden of norovirus gastroenteritis[J]. PLoS One,2016,11(4):e0151219.
[21] 陈艳,刘秀梅,樊永祥,等. 2004年中国食源性疾病暴发事件监测资料分析[J]. 中国食品卫生杂志,2008,20(6):503-506.

Burden of acute gastroenteritis caused by norovirus in Guangdong Province

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