Abstract: Objective To assess the exposure levels of di-（2-ethylhexyl）phthalate （DEHP） and its correlation with lifestyle in college students in Guangzhou.Methods A convenient sampling method was used to recruit college students from East and North campuses of Sun Yat-sen University in Guangzhou. The participant was asked to provide a morning urine sample and complete a questionnaire on general demographic information, dietary habits and use of personal care products. The concentration of mono （2-ethylhexyl） phthalate （MEHP）, a primary metabolite of DEHP in urine samples was determined by gas chromatography-mass spectrometry. The correlation between MEHP concentration levels and influencing factors were analyzed by using univariate and multivariate logistic regressions.Results A total of 123 valid questionnaires matched with urine samples were collected. Of the participants, 44.7% were male and 61.0% were majored in medicine-related specialties. The detection rate of MEHP in urine samples was 90.2%, with a median of 0.49 μg/ml. In the multivariate logistic regression model, the college students who used take-out lunch boxes more than once a week （OR = 2.910） were more likely to have higher MEHP concentrations in the morning urine, while those who used shower gel ≥7 times a week （OR = 0.445） or touched plush toys （OR = 0.282） were less likely to have higher MEHP concentrations in the morning urine.Conclusion The detection rate of MEHP in urine of college students in Guangzhou was high, indicating that the risk of DEHP exposure in this population was higher, and related to personal lifestyle and the use of related plastic products. College students should be encouraged to form a healthy lifestyle, and try to reducing the level of DEHP exposure in the body.

Key words: College students, Urine, Phthalate metabolite, Lifestyle