Abstract: Objective To investigate the compliance of patients with type 2 diabetes mellitus （T2DM） to establish a healthy lifestyle, and to provide a reference for controlling blood glucose levels and promoting blood glucose compliance. Methods T2DM patients aged 45 and over who were diagnosed and treated in a hospital in Nanjing from May 2021 to February 2022 were taken as the objects to monitor compliance with a healthy lifestyle and blood glucose control. The descriptive analysis method was used to analyze the compliance of healthy lifestyle and blood glucose control of T2DM patients, and univariate and multivariate analysis methods were used to analyze the impact of a healthy lifestyle on blood glucose control. Results A total of 1 195 valid objects were included, including 673 males and 522 females. The age ranged from 45 to 76 years old, with a high proportion of 55 to 64 years old （591 cases, 49.46%）. The course of the disease ranged from 6 months to 19 years, with a high proportion of 5 to 9 years （617 cases, 51.63%）. The compliance with a reasonable diet, physical exercise, getting enough sleep, smoking cessation, alcohol restriction, and blood glucose monitoring were 40.75%, 43.43%, 75.65%, 83.01%, 72.13%, and 51.97%, respectively. There were 406 cases that reached the standard of blood glucose, with a compliance rate of 33.97%. Multivariate Logistic regression analysis showed that compliance with reasonable diet （OR＝2.866）, physical exercise （OR＝2.085）, getting enough sleep （OR＝1.982）, alcohol restriction （OR＝1.754）, and blood glucose monitoring （OR＝2.547） were the influencing factors for reaching the standard of blood glucose. Conclusions Compliance with a healthy lifestyle in T2DM patients aged 45 and over is closely related to blood glucose compliance rate. Targeted interventions can be taken according to individual characteristics to help them establish a healthy lifestyle and improve compliance, promote blood glucose compliance and improve the quality of life of T2DM patients.

Key words: Type 2 diabetes mellitus, Health, Lifestyle, Blood glucose, Compliance