Abstract: Objective To explore the status and influencing factors of high-risk behavior among schizophrenic patients in Zhumadian. Methods The primary data of schizophrenic patients under the management of the psychiatry department of a hospital in Zhumadian City were collected as the research objects, and psychiatrists evaluated the high-risk behaviors of the survey subjects. The descriptive analysis method was used to analyze high-risk behavior in schizophrenic patients, and univariate and multivariate analysis methods were used to analyze the influencing factors of high-risk behavior. Results In this survey, 1 084 schizophrenic patients were evaluated for high-risk behavior, 679 were male, accounting for 62.64%, and 405 were female, accounting for 37.36%. The mean age was （47.89±27.65） years old. The evaluation results showed that 78 patients had high-risk behaviors, accounting for 7.19%. Schizophrenic patients who were male （OR=2.704）, aged 18-50 years old （OR=1.555, 2.729, 3.861）, nonlocal census register （OR=1.967）, unemployed or out of work （OR=2.729）, the guardian was not a spouse （OR=3.762, 4.250, 7.822, 8.306, 10.064）, more frequent hospitalizations in the past （OR=3.500, 3.803, 7.621）, and more frequent emergency treatment in the past （OR=10.644, 31.218） were more likely to have high-risk behaviors. Conclusion Schizophrenic patients in Zhumadian have a certain proportion of high-risk behaviors. The male, aged 18-50 years old, and nonlocal census register should actively implement assistance to ensure corresponding social support. For patients hospitalized many times and have had emergency treatment many times, we need to pay more attention.

Key words: Schizophrenia, High-risk behavior, Mental disorders, Personal safety, Disease burden