Abstract: Objective To understand the quality of life and medication compliance of elderly patients with hypertension, and analyze the related factors affecting medication compliance, so as to provide basis for improving medication compliance and blood pressure control of elderly patients with hypertension. Methods A questionnaire survey was conducted on the quality of life and medication compliance of hypertensive patients ≥ 60 years old who underwent a physical examination in a medical examination center of a cadre sanatorium in Hainan Province from March 2018 to June 2019.The quality of life and medication compliance were analyzed by descriptive epidemiological analysis, and univariateand multivariate analysis methods were used to analyze the influencing factors of medication compliance. Results In this study, a total of 1014 hypertensive patients ≥60 years old in Haikou City were investigated. There were 582 males and 432 females, aged 60-83 years old, with an average age of （68.20±5.74） years, and the course of disease was 6 months to 27 years, with an average course of disease of（7.20±3.74） years. There were 432 elderly hypertensive patients with good medication compliance, accounted for 42.60%. The overall score of quality of life was （60.21±13.54）. The scores of each quality of life dimension and the overall scores of elderly patients with good medication compliance were higher than those of patients with poor medication compliance （all P<0.01）. Elderly hypertensive patients who wereolder （OR=0.715）, longer course of disease （OR=0.266）, more than one visit per month （OR=0.674） and combined with other diseases （OR=0.588） were less likely to have good medication compliance. The higher the education level （OR=1.948）, no adverse drug reactions （OR=2.768） and the higher the quality of life score （OR=2.077） were more likely to have good medication compliance. Conclusion Hypertensive patients ≥60 years old in Haikou City have poor medication compliance.Taking corresponding targeted measures to effectively intervene the related factors will help to improve the quality of life and medication compliance of elderly patients with hypertension.

Key words: Elderly hypertension, Quality of life, Medication compliance, Influencing factor