Abstract: Objective To investigate the prevalence and influencing factors of ophthalmopathy among physical examination people aged ≥ 50 years in Wuhan, so as to provide reference for the prevention and treatment of ophthalmopathy. Methods Taking the people aged ≥ 50 years who underwent physical examination in the physical examination center of a hospital in Wuhan from January to December 2020 as the research object, the questionnaire survey, physical examination, blood biochemical index detection and visual acuity examination were carried out. The results were analyzed by descriptive epidemiological analysis method, and the influencing factors of ophthalmopathy were analyzed by univariate and multivariate analysis methods. Results A total of 38 130 physical examination people aged ≥ 50 years in Wuhan were investigated, including 11 702 males and 26 428 females, aged 50 - 89 years, with an average age of 62.9 years. Among them, 12 189 patients with ophthalmopathy were detected, and the prevalence rate was 31.97%. Multivariate analysis showed that female （OR=1.996）, older （OR=1.451）, higher education level （OR=1.357）, higher intensity of eye use （OR=2.793）, out-of-door occupation （OR=1.793）, rural household registration （OR=1.244）, diabetes （OR=6.924）, dyslipidemia （OR=2.221） were risk factors of ophthalmopathy in physical examination people aged ≥ 50 years in Wuhan. Conclusion The prevalence rate of ophthalmopathy in people aged ≥ 50 years in Wuhan is quite high, involving a large variety of risk factors. It is of great significance to take targeted preventive measures for the prevention and treatment of ophthalmopathy.

Key words: Ophthalmopathy, Physical examination, Vision, Influencing factor