Abstract: Objective To investigate the incidence of retinopathy in elderly patients with hypertension and explore its influencing factors. Methods The elderly patients with hypertension treated at the Second Affiliated Hospital of Hainan Medical University, Hainan Provincial Geriatric Hospital, and Hainan West Central Hospital from December 2019 to December 2022 were selected for the study. Eye examination, baseline data investigation, and laboratory index detection were performed on them, and the incidence of retinopathy in elderly patients with hypertension was analyzed by descriptive analysis method. The factors influencing the incidence of retinopathy in elderly patients with hypertension were analyzed by univariate and multivariate analysis methods. Results In this study, a total of 772 elderly patients with hypertension were included for retinopathy investigation, and a total of 402 cases of retinopathy were detected, with a detection rate of 52.07%, among which the detection rate of grade 1 retinopathy was 28.50%, grade 2 retinopathy was 16.71%, grade 3 retinopathy was 4.92%, and grade 4 retinopathy was 1.94%. Multivariate logistic regression analysis showed aged 75-89 years （OR=2.196）, duration of hypertension > 10 years （OR=2.305）, substandard blood pressure control （OR=2.158）, history of diabetes （OR=1.520）, history of dyslipidemia （OR=1.603）, uric acid > 420 μmol/L （OR=1.583）, vascular endothelial growth factor （VEGF）>142 μmol/L （OR=2.458）, hypersensitive C‐reactive protein （hs‐CRP）> 10 mg/L （OR=1.888） were the risk factors for retinopathy in elderly patients with hypertension. Conclusions The incidence of retinopathy in elderly patients with hypertension is high, which is affected by many factors. It is suggested that effective intervention measures can be developed according to the factors of age, disease course, blood pressure control, diabetes, dyslipidemia, uric acid, VEGF, hs‐CRP, etc., to reduce the incidence of retinopathy.

Key words: Hypertension, Elderly people, Retinopathy, Influencing factor