华南预防医学 ›› 2020, Vol. 46 ›› Issue (6): 597-600.doi: 10.12183/j.scjpm.2020.0597

• 论著 • 上一篇    下一篇

广东省诺如病毒急性胃肠炎疾病负担研究

张萌1,2, 向蓥飞3, 陈建千4, 李梦2, 杨芬2, 黄琼2, 张永慧1,2   

  1. 1.中山大学,广东 广州510080;
    2.广东省疾病预防控制中心;
    3.广州市越秀区疾病预防控制中心;
    4.佛山市三水区疾病预防控制中心
  • 收稿日期:2019-12-16 出版日期:2020-12-20 发布日期:2021-01-12
  • 通讯作者: 张永慧,E-mail:zyh@cdcp.org.cn
  • 作者简介:张萌(1983-),男,在读硕士研究生,主管医师,研究方向:传染病预防控制

Burden of acute gastroenteritis caused by norovirus in Guangdong Province

ZHANG Meng1,2, XIANG Ying-fei3, CHEN Jian-qian4, LI Meng2, YANG Fen2, HUANG Qiong2, ZHANG Yong-hui1,2   

  1. 1. Sun Yat-sen University,Guangzhou 510080,China;
    2. Guangdong Provincial Center for Disease Control and Prevention;
    3. Guangzhou Yuexiu District Center for Disease Control and Prevention;
    4. Foshan Sanshui District Center for Disease Control and Prevention
  • Received:2019-12-16 Online:2020-12-20 Published:2021-01-12

摘要: 目的 对广东省诺如病毒急性胃肠炎的流行病学负担进行评估,为制定或调整疫情防控策略提供科学依据。方法 结合广东省2013-2017年感染性腹泻病监测数据、与腹泻病相关的监测数据和调查结果,采用发病率、伤残调整寿命年(DALYs)和网络报告与实际发病数的比值等指标对广东省诺如病毒急性胃肠炎的流行病学负担进行评估。结果 2013-2017年广东省诺如病毒急性胃肠炎年均发病数为310.27万人次/年(253.59~403.76万人次/年);估算年均就诊病例数为127.83万人次/年(104.48~166.35万人次/年);估算年均住院病例数为383人次/年(313~499人次/年)。网络报告诺如病毒急性胃肠炎发病数与实际发病数之比为1∶1 203(1∶860~1∶1 771)。年均总负担为19 200.55 DALYs(16 919.20~25 001.83 DALYs),平均负担为0.18 DALYs/千人年(0.15~0.23 DALYs/千人年)。结论 广东省诺如病毒急性胃肠炎疾病负担相对较高,需要有针对性的加强预防控制管理以及宣传教育。

关键词: 诺如病毒, 疾病负担, 急性胃肠炎

Abstract: Objective To estimate the epidemiological burden of norovirus (NoVs) acute gastroenteritis in Guangdong Province, so as to provide scientific basis for formulating or adjusting epidemic prevention and control strategies.Methods Using data from infectious diarrheal disease surveillance, diarrhea related surveillance, and investigation results in Guangdong Province from 2013 to 2017, the epidemiological burden of NoVs acute gastroenteritis was assessed by morbidity, disability adjusted life years ( DALYs), and the ratio of the number of cases reported by the internet to the number of actual incidence cases.Results The total number of cases of NoVs infectious gastroenteritis was 3.1027 million persons/year (2.535 9-4.037 6 million persons/year) in Guangdong Province from 2013 to 2017. The annual average number of medical visits was estimated to be 1.278 3 million persons/year (1.044 8-1.663 5 million persons/year). The annual average number of inpatients was estimated to be 383 persons/year (313-499 persons/year). The ratio of the number of cases reported by the internet to the number of actual incidence cases was 1∶1 203 (1∶860-1∶1 771). The average total annual burden was 19 200.55 DALYs(16 919.20-25 001.83 DALYs), and the per capita burden was 0.18 DALYs/thousand person-years (0.15-0.23 DALYs/thousand person-years).Conclusion The burden of acute gastroenteritis caused by NoVs was high in Guangdong Province. It is necessary to strengthen the management of prevention and control, as well as the publicity and education.

Key words: Norovirus, Disease burden, Acute gastroenteritis

中图分类号: 

  • R183.4