Abstract: Objective To investigate the occurrence and risk factors of diabetic retinopathy （DR） in patients with type 2 diabetes （T2DM）.Methods A T2DM patient who was treated for the first time in an outpatient clinic of a hospital in Nanjing from June 2017 to May 2019 was selected as the research object to conduct investigation of basic information and disease information, physical examination, laboratory index testing and DR examination.Descriptive epidemiological analysis was used to analyze the DR in T2DM patients, and the influencing factors were analyzed by univariate and multivariate analysis methods.Results A total of 1 248 T2DM patients were analyzed. Males accounted for 45.99% and females accounted for 54.01%. 348 cases of DR were detected, with a detection rate of 27.88%, mostly moderate （201 cases, 57.75%）. Multivariate logistic regression analysis showed that T2DM patients with the older the age （OR_50~59=2.259, OR_60~69=2.321, OR_70~79=5.388）, the course of T2DM ≥5 years （OR=6.372）, the use of insulin therapy （OR=2.753）, HbA1c abnormality（OR=4.658）, hypertension （OR=4.565）, urinemicroalbumin （OR=3.034）, and LDL-C abnormality（OR=3.554） had a higher risk of DR.Conclusion The incidence rate of DR in T2DM patients is relatively high, and associated with age, course of disease, insulin therapy, HbA1c abnormality, hypertension and other factors. Monitoring of T2DM patients with risk factors and active targeted intervention measures can reduce the risk of DR and improve the quality of life of patients.

Key words: Type 2 diabetes, Diabetic retinopathy, Complications, Prevalence, Influencing factor