Abstract: Objective To investigate the status of pre-hypertension among young and middle-aged people undergoing physical examination in Zhengzhou City, and analyze its influencing factors, so as to provide scientific basis for the comprehensive prevention and treatment of hypertension and the selection of intervention measures in local specific population. Methods From September 2018 to August 2020, the young and middle-aged people aged 18-59 years old in Zhengzhou City who underwent physical examination in the physical examination center of a hospital in Henan Province were selected as the research objects to investigate the current situation of pre-hypertension, and the influencing factors of pre-hypertension were analyzed by univariate and multivariate analysis. Results There were 6 572 males and 5 988 females in the 12 560 subjects aged 18-59 years old in Zhengzhou City. The average age was （37.20 ± 5.16） years old. The majority of them were 25-44 years old, accounting for 58.91%. Among them, 4 486 cases of pre-hypertension were detected, the detection rate was 35.72%;1 949 cases of hypertension were detected, the prevalence rate was 15.52%. The older age （OR=1.370）, higher BMI （OR=2.054）, smoking （OR=1.065）, family history of hypertension （OR=1.353）, hypercholesterolemia （OR=1.507）, hypertriglyceridemia （OR =1.443） and low HDL-C （OR=1.157） in young and middle-aged persons who hada higher risk of pre-hypertension detection. Conclusion The detection rate of pre-hypertension is high in young and middle-aged people undergoing physical examinationin Zhengzhou City. Overweight and obesity are the most obvious influencing factors. Health education should be strengthened for young and middle-aged people with overweight, family history of hypertension, smoking and dyslipidemia, so as to meet the target of prevention and control of hypertension.

Key words: Pre-hypertension, Prevalence, Young and middle-aged population, Risk factor