Abstract: Objective To investigate the status of medication compliance in patients with essential hypertension, and to analyze the influencing factors. Methods Taking patients with essential hypertension in hospitals in Zhengzhou as the research objects, a convenient sampling method was used to carry out a survey on the medication compliance of patients with essential hypertension in public hospitals from April to October 2019. Descriptive epidemiological analysis method was used to analyze medication compliance, and univariate and multivariate analysis method was used to analyze its influencing factors. Results A total of 3 138 hypertensive patients were investigated, aged 45-80 years old, with an average ageof （68.93±9.39） years. Males accounted for 58.4%, those with hypertension for 5-10 years accounted for 43.8%, those who took ≥3 kinds of drugs accounted for 25.8%, and 78.4% had no adverse drug reactions. There were 1 621 cases with good medication compliance, accounting for 51.7%, and 1 517 cases with poor medication compliance, accounting for 48.3%. The main reasons for poor medication compliance were forgetting the medication experience （46.4%）, sometimes not taking medication （24.6%）, discontinuing medication when symptoms improved accounted for 22.9%, and stopping medication when symptoms became worse accounted for 6.0%. The essential hypertensive patients with bachelor degree or above （OR=1.976）, higher family monthly income （OR=3.543） and medical insurance payment （OR=1.522） were more likely to have good medication compliance, while the patients living alone （OR=0.305） and more types of medication （OR=0.694） were less likely to have good medication compliance. Conclusion The medication compliance of patients with essential hypertension in Zhengzhou is poor. Education level, economic situation, living alone, medical expenses payment method and medication type are the influencing factors of poor medication compliance.

Key words: Hypertension, Medication, Medication compliance, Influencing factor