Abstract: Objective To understand the prevalence of Alzheimer's disease （AD） in Fengtai District of Beijing and analyze its influencing factors, so as to provide scientific basis for formulating health management policies. Methods Convenience sampling method was used to select permanent residents ≥ 60 years old in Fengtai District of Beijing for AD prevalence and related factors investigation, and the Simple Mental State Examination Scale （MMSE） was used to screen the elderly for AD. The positive cases were diagnosed by psychiatrists according to the diagnostic criteria. Descriptive epidemiological method was used for analysis, and univariate and multivariate logistic regressions were used to analyze the influencing factors of AD. Results A total of 5 901 people aged 60 - 92 years old in Fengtai District were investigated, mainly 70 - 79 years old, accounting for 39.3%. The ratio of male to female was 0.96∶1. Three hundred and nineteen cases of AD were diagnosed, the prevalence rate was 5.41%. Binary logistic regression analysis showed that age increased （OR=2.284）, unmarried/widowed/divorced （OR=2.487）, introversion （OR=2.298）, excessive drinking （OR=12.820）, low level of social support （OR =1.514）, dyslipidemia （OR=2.512） were the risk factors of AD in the elderly; interest （OR=0.299） and regular physical exercise （OR=0.045） were the protective factors. Conclusion The prevalence of AD in the elderly in Fengtai District of Beijing is relatively high, and with the increase of age, the prevalence increases. There are many risk factors of AD, and relevant departments should pay attention to it.

Key words: Alzheimer's disease, Cognitive impairment, Prevalence rate, Influencing factor