Abstract: Objective To analyze the status of low birth weight （LBW） of newborns in Nanning, Guangxi, and to study high-risk factors to provide a basis for formulating targeted maternal and child health care measures in this area. Methods Based on the “Guangxi Gui Women and Children's Health Management Information System”, the demographic characteristics, pregnancy conditions, obstetrics and delivery records and neonatal data of pregnant and lying-in women established in Nanning, Guangxi in 2018 were collected. The descriptive epidemiological analysis method was used to analyze the occurrence of LBW, and single and multiple factor analysis methods were used to analyze the high-risk factors of LBW. Results There were 47 339 registered newborns in Nanning, Guangxi in 2018, including 3 229 cases of LBW. The incidence of LBW was 6.82%. The results of multivariate analysis showed that the pre-pregnancy weight of pregnant women was too light （OR=1.211）, insufficient weight gain during pregnancy （OR=3.423）, high-risk pregnancy （OR=1.920）, multiple pregnancy （OR=9.533）, hemoglobin concentration in early pregnancy <110 g/L （OR=1.251）, and premature delivery （OR=31.860） were risk factors for neonatal LBW. Conclusion The incidence of LBW in Nanning, Guangxi is equivalent to the national average. Pre-pregnancy BMI, weight gain during pregnancy, preterm birth, high-risk pregnancy, multiple pregnancy, and hemoglobin concentration in early pregnancy are high-risk factors for LBW.

Key words: Newborn, Low birth weight, Incidence, High risk factor