Abstract: Objective To analyze the cancer incidence and mortality in Zhuhai in 2016. Methods Based on data of cancer incidence and deaths in Zhuhai in 2016, the incidence and mortality rates, ranking and constituent ratio were calculated. The Joinpoint Program was used to analyze the trend of cancer incidence and mortality from 2010 to 2016. Results The crude cancer incidence rate was 286.41/10⁵ in Zhuhai in 2016, with Chinese age-standardize rate of 222.69/10⁵. The main cancers were female breast cancer, lung cancer, colorectal cancer, liver cancer, and cervical cancer. The top 10 malignant tumors accounted for 72.75% of all cancers. The crude mortality rate of cancer was 116.16/10⁵, with Chinese age-standardize rate of 88.83/10⁵. The most common causes of cancer deaths were ranked as lung cancer, liver cancer, colorectal cancer, female breast cancer, and stomach cancer. The top 10 cancer deaths accounted for 80.27% of all cancer deaths. During 2010-2016, the cancer incidence and mortality in Zhuhai showed a significant upward trend （incidence： APC=3.27%, P<0.05; mortality： APC=3.03%, P<0.01）. Conclusion The cancer incidence and mortality showed an increasing trend in Zhuhai. Female breast cancer, lung cancer, colorectal cancer, liver cancer and cervical cancer are the main cancers to be prevented and treated.

Key words: Malignant tumor, Cancer registration, Incidence, Mortality