Abstract: Objective To assess the disease burden of contact dermatitis in China and other Asian countries and regions in order to better promote human health. Methods Data on contact dermatitis were obtained from the Global Burden of Disease Database （GBD2019）. Disability-adjusted life years （DALYs） and age-standardized rates （ASRs, rates per 100 000 persons） for prevalence were used as descriptors for disease burden, and estimated annual percentage changes （EAPC, %） was used to describe trends in the burden of disease from 1990 to 2019. Results From 1990 to 2019, both DALY rates and prevalence of contact dermatitis in Asia showed an increasing trend （EAPC>0, 95%UI>0）, and both DALY rates and prevalence in China increased year by year （EAPC>0, 95%UI>0）. DALY rates and prevalence were higher in Asia than globally, higher in China than in Asia, and higher in females than in males. In 2019, the age group with the highest DALY rate and prevalence were both 70-74 years old, the country with the highest DALY rate was Philippines （34.94/100 000） and the lowest was Israel （7.28/100 000）, and the country with the highest prevalence was Philippines （1 406.92/100 000） and the lowest was Israel （289.63/100 000）. Conclusion The disease burden of contact dermatitis in Asia is steadily increasing, and countries and territories need to raise awareness of contact dermatitis according to the actual situation and prevent the occurrence of contact dermatitis.

Key words: Contact dermatitis, Disease burden, Disability-adjusted life years, Prevalence