Abstract: Objective To investigate the high-risk behavior of registered schizophrenic patients in the Fuyang area and its influencing factors. Methods A total of 1 264 patients with schizophrenia registered in the Mental Health Prevention and Treatment Information Management System of Fuyang City from January 2018 to December 2021 were selected. Demographic data, clinical data, and follow-up information were collected, and univariate and multivariate Logistic regression were used to analyze the factors affecting the high-risk behavior of patients with schizophrenia. Results Among the 1 264 patients with schizophrenia, 703 were males and 561 were females, with an average age of （42.15±14.06） years. The risk assessment of 102 patients was 3-5, and the incidence of high-risk behavior was 8.07%. The results of multivariate Logistic regression analysis showed that divorce/widowed （OR=2.03）, unmarried （OR=5.07）, not taking antipsychotic drugs （OR=3.16）, previous history of high-risk behavior （OR=3.12）, not participating in annual health checkup （OR=2.67）, and the number of community visits ≥5 times per month （OR=1.30） were risk factors for high-risk behavior in patients with schizophrenia. The number of community visits 1-2 times （OR=0.57） and 3-4 times （OR=0.58） per month were protective factors for high-risk behavior in patients with schizophrenia. Conclusion It is necessary to strengthen the comprehensive evaluation of the factors related to high-risk behavior in schizophrenia patients, and adopt the classification management in time, to effectively reduce the incidence of high-risk behavior.

Key words: Schizophrenia, High-risk behavior, Influencing factor