Abstract: Objective To investigate the status of Helicobacter pylori infection among residents in Xi’an and analyze the correlation between Helicobacter pylori infection and residents’ lifestyle. Methods A multi-stage sampling method was used to select community residents in Xi’an from January to December 2022 for a questionnaire survey and a ¹⁴C urea breath test to evaluate the status of Helicobacter pylori infection. Descriptive analysis was used to analyze the status of Helicobacter pylori infection among residents, and univariate and multivariate analysis methods were used to analyze the correlation between Helicobacter pylori infection and lifestyle in this population. Results A total of 1 089 residents were included for analysis, and the infection rate of Helicobacter pylori was 43.62% （475/1 089）. Multivariate logistic regression analysis showed that older age （OR=1.340）, overweight or obese （BMI≥24.0 kg/m²） （OR=1.146）, lower education level （OR=0.453）, predominantly mental labor （OR=1.745）, smoking （OR=1.245）, alcohol consumption （OR=2.203）, daily breakfast （OR=0.378）, irregular meals （OR=4.595）, and frequent consumption of milk or yogurt （OR=4.035） were independent factors affecting Helicobacter pylori infection. Conclusion The prevalence of Helicobacter pylori infection among residents in Xi’an is relatively high, and it is closely related to lifestyle factors such as smoking, drinking, and dietary habits.

Key words: Digestive system disease, Helicobacter pylori, Healthy behavior, Lifestyle